Oral Controlled Release Formulation Design and Drug by Hong Wen, Kinam Park

By Hong Wen, Kinam Park

This ebook describes the theories, purposes, and demanding situations for various oral managed unlock formulations. This e-book differs from so much in its specialize in oral managed unlock formula layout and approach improvement. It additionally covers the comparable components like preformulation, biopharmaceutics, in vitro-in vivo correlations (IVIVC), caliber by way of layout (QbD), and regulatory concerns.

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Chem. Pharm. Bull. 1992;40:3036–3041. 71. Youan BC. Chronopharmaceutics; gimmick or clinically relevant approach to drug delivery? J. Control. Release 2004; 98:337–353. 72. Wilding IR. Site specific delivery in the gastrointestinal tract. Crit. Rev. Ther. Drug Carrier Syst. 2000;17:557–622. 31 73. Urquhart J. Controlled drug delivery: therapeutic and pharmacological aspects. J. Intern. Med. 2000;248:357–376. 74. Rabinow BE. Nanosuspensions in drug delivery. Nat. Rev. Drug Discov. 2004;3:785–796.

Ibekwe VC, Fadda HM, Parsons GE, Basit AW. A comparative in vitro assessment of the drug release performance of pHresponsive polymers for ileo-colonic delivery. Int. J. Pharm. 2006;308:52–60. 33. Friend DR. New oral delivery systems for treatment of inflammatory bowel disease. Adv. Drug Del. Rev. 2005;57:247–265. 34. Siepmann F, Siepmann J, Walther M, MacRae RJ, Bodmeier R. Polymer blends for controlled release coatings. J. Control. Release 2008;125:1–15. 35. htm. 36. H. Sympathomimetic preparation.

Lee PI. Initial concentration distribution as a mechanism for regulating drug release from diffusion controlled and surface erosion controlled matrix systems. J. Control. Release 1986;4:1–7. 67. editor. Diffusion-controlled matrix systems. In Kydonieus A,editor. Treatise of Controlled Drug Delivery: Physicochemical Basis, Optimization, Applications, Marcel Dekker, 1992, pp. 155–197. 68. Xu X, Lee PI. Programmable drug delivery from an erodible association polymer system. Pharm. Res. 1993;10:1144–1152.

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