Microangiopathy by R. De Cristofaro

By R. De Cristofaro

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2011). Ang II acts also like growth factor regulating the cell growth and tissue expansion what can lead to cell hyperthrophy and fibrotic changes of tissues. 7 Risk factors An important role of diabetes compensation in development of chronic diabetic complications was proved by multicentric randomized study Diabetes Control and Complication Trial (DCCT) between 1983 and 1993 (DCCT Research Group, 1993). 1441 patients with DM type 1 (diabetes duration 1 – 15 years) were enrolled to the study, divided into two groups according to the treatment by either conventional or intensified insulin regimen.

Am J Obstet Gynecol, 2006. 195(3): p. 723-8. J. G. Cunningham, Hypertension in pregnancy. J Am Soc Hypertens, 2010. 4(2): p. 68-78. R. N. George, Evaluation of women with clinically suspected thrombotic thrombocytopenic purpura-hemolytic uremic syndrome during pregnancy. J Clin Apher, 2001. 16(4): p. 202-9. , Preeclampsia: a renal perspective. Kidney Int, 2005. 67(6): p. 210113. , Hemolytic uremic syndrome with hypocomplementemia and deposits of IgM and C3 in the involved renal tissue. Clin Nephrol, 1981.

Slit lamp examination can investigate the spatial relations between retina and vitreous. The recommendation of complication screening is presented in table 4. Retinopathy Recommendation of screening frequency Once a year in children at the age > 11 years with DM duration > 2 years or at the age 9 years in children with DM duration ≥ 5 years Once a year in children at the age > 11 years with DM duration > 2 years or at the age 9 years in children with DM duration ≥ 5 years Methods Therapy Ophtalmoscopy in mydriasis or photography of fundus Improvement of DM compensation laser therapy Albumin Improvement of DM concentration in the compensation Nephropathy first morning urine therapy by ACE portion or albumin / inhibitors, decrease creatinin ratio of BP History, physical Improvement of DM Neuropathy Consensus was not achieved examination compensation Serum lipids every 5 Improvement of DM Macrovascular At the age 12 years years, blood pressure compensation, complications once a year decrease of BP Table 4.

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