Lipid Peroxides in Biology and Medicine by Kunio Yagi

By Kunio Yagi

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1, 92 (1973). , J . Biol. Chem. 247, 188 (1972). , J . Biol. Chem. 246, 6886 (1971). , J . Biol. Chem. 233, 1581 (1958). , J . Biol. Chem. 246, 7119 (1971). , Fed. Proc. 28, 346 (1968). , J. Biol. Chem. 244, 6049 (1969). Nat. Acad. A. 68, 1024 (1971). , Biochem. Biophys. Res. Commun. 58, 479 (1974). , Res. Commun. Chem. Path. Pharmacol. 11, 31 (1975). , J . Biol. Chem. 249, 2447 (1974). , Science 181, 456 (1973). , Ann. Y. Acad. Sci. 258, 221 (1975). Goodman, J . , Biochem. Biophys. Res. Commun.

All rights of reproduction in any form reserved. ISBN 0-12-768050-0 Lars Ernster et al. c ν Asc or b a t e — * F e * 0 — • H 0 ,| \ - — I TPNH —• Fp 2 EDTA ι PC MB rROH - S H " — • Fe 0 : K ADP > 5ΚΓ, Lipid - DPPD, ocTM • Lipid-0 I I MA MITOCHONDRIA & MICROSOMES MICROSOMES Fig. 1. Schematic representation of lipid peroxidation linked to ascorbate or TPNH (NADPH) oxidation in microsomes and mitochondria. From Hochstein and Ernster (1). known as NADPH-cytochrome c reductase, subsequently identified as NADPH-cytochrome P - ^ 5 0 reductase.

Commun. 8 7 , 192. , and Hayaishi, 0. (1981) Arch. Biochem. Biophys. 206, 271. , and Samuelsson, B. (1967) ^J. Biol. Chem. 242, 5336. Nugteren, D. H. (1975) Biochim. Biophys. Acta 380, 299. , Hamberg, Μ. , and Samuelsson, B. (1976) J_. Biol. Chem. 251, 7816. , and Samuelsson, B. (1980) Proc. Natl. Acad. Sci. USA 77_, 2014. Goetzl, E. , and Gorman, R. R. (1978) j;. Immunol. 120, 526. Desai, I. D. , and Tappel, A. L. (1963) _J. Lipid Res. _4, 204. Tappel, A. L. (1973) Fed. P r o c J32, 1870. , and Malmsten, C.

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