Fortschritte der Arzneimittelforschung / Progress in Drug by H. Herbst, N. J. Harper, E. Schlittler, J. Druey, A. Marxer,

By H. Herbst, N. J. Harper, E. Schlittler, J. Druey, A. Marxer, H. Grasshof, J. C. Arcos, M. Arcos (auth.), Ernst Jucker (eds.)

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10. 1958; ref. Arzneimittelforsch. 8, 779 (1958). [105J E. TUBARO, L. PIZZOGLIO und E. RAFFALDONI, Boll. chim. farmac. 97, 9 (1958). [106J H. WALTz, Med. I-Gin. 53, 419 (1958). [107J H. HASCHEK und R. EHRENREICH, Wiener Med. Wschr. 108, 197 (1958). [108J G. G. JACKSON und H. G. GRIEBLE, Ann. New York Acad. Sci. 69, 493 (1957). WALKER und M. HAMBURGER, Ann. New York Acad. Sci. 69,509 (1957). [110J M. H. LEPPER und A. J. SIMON, Ann. New York Acad. Sci. 69, 485 (1957). [l11J S. E. AHRENS und E. A.

Eingehender wurden das Kupplungsprodukt mit Thymol, das 4,4'-Bis-(Pisopropyl-m-kresylazo)-diphenylsulfon (Sulfon D) (IX), sein Di-Silbersalz und die Mischung beider Substanzen (Diatoxargentique) gegen Tuberkulose und Lepra gepriift. Die Angaben iiber die Wirkung bei Lepra schwanken; FLOCH [73J fand es weniger als DDS wirksam, RIST [74J konnte mit Gaben von 200 mg taglich eine Wirkung feststellen, und TZANCK [75J konnte 15 therapieresistente Falle ohne wesentliche Nebenwirkungen giinstig beeinflussen.

PONCI, Farmaco, Ediz. sci. 11, 158 (1956). [64J R. PONCI und F. GIALDI, Farmaco, Ediz. sci. 11, 151 (1956). [65J F. GIALDI und R. PONCI, Farmaco, Ediz. sci. 12, 305 (1957). [66J S. D. SOBELL und A. ARNOLD, Proc. Soc. expo BioI. Med. 90, 594 (1955). [67J A. P. 2 649460; A. P. 2684 372; A. P. 2 592 529. [68J T. N. OLENEWA, Probleme d. Tuberkulose 36,56 (1958), ref. C. 1959,8237. [69J H. GEIGER und B. A. FINKELSTEIN, Schweiz. med. Wschr. 84, 1063 (1954). G. ALCOZER und G. LINDIARDI, Arch. «E. Maragliano» Patol.

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