By Pamela Korsmeyer, Henry R. Kranzler
A follow-up to the 2001 award-winning moment variation, the Encyclopedia of gear, Alcohol, and Addictive habit, third version, will replace and extend upon the social, scientific, criminal, and political concerns relating to medicines and alcohol and linked behaviors. The fast velocity of study within the fields of substance abuse and non-substance abuse addictions seeing that booklet of the second version warrants a brand new exploration of the sector. within the MacMillan Reference united states culture, a board of famous students within the fields of substances, alcohol, and dependancy deliver new scholarship in the self-discipline to the set along dialogue of subject matters usually pointed out in today's media. insurance of those thoughts past the U.S. - in the course of the ecu Union, Asia, and past - will considerably extend. information through the set should be revisited and punctiliously up-to-date, and the A-Z access association might be maintained. a powerful cumulative index will whole the paintings.
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Extra resources for Encyclopedia of Drugs, Alcohol & Addictive Behavior, Volume 2: D-L
GALE, CENGAGE LEARNING BY GGS INFORMATION Often, however, the response (ordinate) is plotted against the logarithm of the drug concentration (abscissa) to transform the dose-response relationship into a sigmoidal curve. This transformation makes it easier to compare different doseresponse curves—since the scale of the drug concentration axis is expanded at low concentrations where the effect is rapidly changing, while compressing the scale at higher doses where the effect is changing more slowly (see Figure 2).
Hendriks, D. , & Michalovic, J. G. (1992). The incidence and role of drugs in fatally injured drivers (Report No. DOT 808 065). S. Department of Transportation. S. Department of Health and Human Services. (1987). S. Congress on alcohol and health. Rockville, MD: Author. S. Department of Transportation. (1968). Alcohol and highway safety: A report to the Congress. S. Government Printing Office. S. Department of Transportation, National Highway Traffic Safety Administration. Traffic safety facts 2005: A compilation of motor vehicle crash data from the Fatality Analysis Reporting System and the General Estimates System (Report No.
A certain degree of cough suppression), and the concentration of the drug is plotted against the percentage of a specific population in which the drug produces the effect. The median effective dose (ED50 or the dose at which 50% of the individuals exhibit the specified quantal effect) and the median lethal dose (LD50 or the dose at which death is produced in 50% of the experimental animals in preclinical studies) can be estimated from quantal dose-effect curves. With this type of curve, the relative effectiveness of various drugs for producing a desired or undesired effect, as well as the relative safety between various drugs, can be determined.