Advances in Nutritional Research by S. Harvey Mudd (auth.), Harold H. Draper (eds.)

By S. Harvey Mudd (auth.), Harold H. Draper (eds.)

Volume four of Advances in dietary study displays the elevated value that lately has been connected to food in lots of fields of medical drugs. This heightened curiosity in nutrients stems from the demonstration that the consumption of particular food can have far-reaching outcomes, not just for regular metabolism, but in addition for metabolic procedures affecting medical or subclinical disorder. Conversely, many sickness states were proven to have formerly unrecognized results on nutrient functionality and metabolism. as well as issues of visible relevance to human medical meals, this quantity includes chapters facing the food of cells grown in tradition and of species that can supply insights into dietary issues of guy. To­ gether with its predecessors, quantity four offers graduate scholars and estab­ lished investigators with authoritative debts of the prestige of study on more than a few subject matters of present curiosity in experimental and medical foodstuff. vii Contents bankruptcy 1. Vitamin-Responsive Genetic Abnormalities .......... . S. Harvey Mudd 1. Introduction.............................................. 1 2. historic viewpoint ...................................... 2 three. Genetic Abnormalities at the moment identified to Be diet Responsive. three four. Mechanisms Underlying nutrition Responsiveness. . . . . . . . . . . . . . . . 7 4.1. Defects within the Processing of a diet sooner than Its interplay in Cofactor shape with a specific Apoenzyme ........ 7 4.2. Defects particularly Apoenzymes that engage with the Cofactor types of supplements. . . . . . . . . . . . . . . . . . sixteen . . . . . .

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1972, Lysyl-protocollagen hydroxylase deficiency in fibroblasts from siblings with hydroxylysine-deficient collagen, Proc. Natl. Acad. Sci. A. 69:2899. Lampkin, B. , and Maurer, A. , 1967, Congenital pernicious anemia with coexistent transitory malabsorption of vitamin 8 12 , Blood 30:495. , 1970, Congenital malabsorption of folate, Am. 1. Med. 48:580. , 1977, Congenital malabsorption of folate associated with mental retardation, in: Nutritional Deficiency Secondary to Inborn Errors of Metabolism Its Relation to Physical and Mental Development (N.

Morrow, G. , and Whelan, D. , 1978, A new variant of 32 S. Harvey Mudd methylmalonic acidemia-{jefective coenzyme-apoenzyme binding in cultured fibroblasts, Clin. Chim. Acta 85:67. Mudd, S. , 1971, Pyridoxine-responsive genetic disease, Fed. Proc. 30:970. Mudd, S. , 1974a, Inborn errors of metabolism. Vitamin-responsive genetic disease, J. Clin. Pathol. ) 8:38. Mudd, S. , 1974b, Homocystinuria and homocysteine metabolism: Selected aspects, in: Heritable Disorders of Amino Acid Metabolism (W. L.

1979, Megaloblastic anemia as a result of an abnormal transcobalamin II (Cardeza), J. Clin, Invest. 64: 1253. 30 S. Harvey Mudd Hillman, R. , Keating, J. , and Williams, J. , 1978, Biotin-responsive proprionic acidemia presenting as the rumination syndrome, 1. Pediatr. 92:439. Hitzig, W. , Pluss, H. , 1974, Hereditary transcobalamin II deficiency: Clinical findings in a new family, 1. Pediatr. 85:622. Hommes, F. , Polman, H. , and Reerink, J. , 1968, Leigh's encephalomyelopathy: An inborn error of gluconeogenesis, Arch.

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