Advances in Immunology, Vol. 64 by Frank J. Dixon

By Frank J. Dixon

Learn Institute of Scripps medical institution, l. a. Jolla. examine within the box. For investigators. 19 members, 6 U.S.

Show description

Read Online or Download Advances in Immunology, Vol. 64 PDF

Similar biology books

Osteoporosis: Methods and Protocols

In recent times, the research of bone cells and tissues on the mobile and molecular degrees in numerous types has revolutionized the sector. In Osteoporosis: equipment and Protocols, prime scientists from all over the world proportion their step by step laboratory protocols for learning bone biology. the subjects coated during this quantity contain in vitro versions, in vivo versions applied for drug trying out, tissue engineering and osteoporosis stories in both gender, cutting-edge molecular recommendations to evaluate unmarried genes or for worldwide genomic research, strong imaging options, and plenty of extra.

Molecular Mechanisms in Bioenergetics

This ebook summarises present wisdom of the constitution, function,biosynthesis and law of energy-transducing enzymes inmitochondria, chloroplasts and micro organism. all of the twenty chapters is written by means of best specialists of their box, and Prof. Ernster has ensured that the booklet as an entire supplies a well-integrated photograph of the current country of information of the sector at its various degrees and complexities.

Extra info for Advances in Immunology, Vol. 64

Sample text

Immunol. 151, 1193-1204. , and Townsend, A. (1995). Genes encoded in the major histocompatibility complex affecting the generation of peptides for TAP transport. Eur. /. lmmunol. 25, 554-562. Ciechanover, A. (1994). The ubiquitin-proteasome proteolytic pathway. Cell 79, 13-21. , and Goldberg, A. L. (1996). Structure and functions of the 20s and 26s proteasomes. Annu. Rev. , 65, 801-847. Cox, J. , Bennink, J. , and Yewdell, J. W. Presentation of endogenous antigen is not affected by inactivation of E l ubiquitin-activating enzyme in temperaturesensitive cell lines.

Slaughter, C. , and DeMartino, G. N. (1992). ]. Biol. C h m . 267, 10515-10523. Michalek, M. , Erant, E. , Goldberg, A. , and Rock, K. L. (1993). A role for the ubiquitin-dependent proteolytic pathway in MHC class I-restricted antigen presentation. Nature 363, 552-554. Momburg, F. , Powis, S. , Butcher, G. , Howard, J. , and Hgmmerling, G. J. (1992). Proteasome subunits encoded by the major histocompatibility complex are not essential for antigen presentation. Nature 360, 174-177. Momburg, F.

Joining of V to J regions is thus directed toward making functionally useful genes, whereas the biologically futile joining of one V to another V, or a J to a J, is rare. Recombination makes a junction of two coding segments (a coding joint) and in parallel produces a heptamer to heptamer fusion of the signals (a signal joint). Depending on the orientation of the signals, the rearrangement can lead to either a deletion or an inversion of the intervening DNA. In the most common arrays at the antigen receptor loci, the coding joint is retained in the chromosome and a circular DNA molecular containing the signal joint is excised and subsequently lost from the cells.

Download PDF sample

Rated 4.59 of 5 – based on 30 votes