By J B McFerran; M S McNulty; Commission of the European Communities. Coordination of Agricultural Research
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Additional info for Acute virus infections of poultry : a seminar in the CEC Agricultural Research Programme, held in Brussels, June 13-14, 1985
14, 173-176. M. M. 1985b. Efficacy of avian influenza neuraminidase - specific vaccines in chickens. , in Press. , Becht, H. and Orlich, M. 1974. The significance of influenza virus neuraminidase in immunity. J. gen. , 22, 35-41. 45 EXPERIMENTAL VACCINATION OF CHICKENS AGAINST AVIAN INFLUENZA SUBTIPE H5 WITH AN INACTIVATED OIL EMULSION VACCINE B. G. O. 5 ~l of two inactivated influenza vaccines prepared using the virulent A/tern/S. Africa/6l (H5N2) strain were injected subcutaneously into five week old SPF chicks.
Iii) Serotypes No attempt has been made to produce a definition of a serotype for the avian paramyxoviruses. Initially differentiation into serogroups was based on serological tests such as the haemagglutination inhibition (HI) test, but, in more recent years, other tests and virus properties have been used. Using HI tests several authors have reported minor crosss reaction between P}N-1 and P}N-4 serotypes (Kessler et at, 1979); P}W-l and P}W8, P}W-1 and P}W-9, P}N-3 and P}N-8, P}W-3 and P}W-9, P}N-4 and P}N-8 54 at, 1983b); PHV-7?
Virus was recovered 3 days after challenge from faeces from all groups. The virus titre varied from 0 (recovery from undiluted faeces) in the nonvaccinated birds and those vaccinated with 125 pI of vaccine A to 1 in faeces from birds vaccinated with 125 pI of vaccine B. v. 11 out of 13 non-vaccinated birds died. None out of 15 birds vaccinated with 500 pI of vaccine B showed 50 disease symptoms. 5 pl of this vaccine, some mortality and morbidity occurred (table 2). On the other hand 4 out of 14 birds vaccinated with 500 pI of vaccine A died.